Conditions

The FDA initially approved XTANDI, an oral, once-daily androgen receptor inhibitor, in August 2012 for use in patients with metastatic CRPC who previously received docetaxel (chemotherapy). The new indication approves XTANDI for use in men with metastatic CRPC who have not received chemotherapy. Metastatic CRPC is defined as a cancer that has spread beyond the prostate gland and has progressed despite treatment to lower testosterone (i.e., with a gonadotropin-releasing hormone (GnRH) therapy or…

The U.S. Food and Drug Administration approved Cologuard, the first stool-based colorectal screening test that detects the presence of red blood cells and DNA mutations that may indicate the presence of certain kinds of abnormal growths that may be cancers such as colon cancer or precursors to cancer. Cologuard offers people 50 and older at average risk for colorectal cancer an easy-to-use screening test they can do in the privacy of their own home. Colorectal cancer was the third most…

The U.S. Food and Drug Administration today approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight management in addition to a reduced-calorie diet and physical activity. The drug is approved for use in adults with a body mass index (BMI) of 30 or greater (obesity) or adults with a BMI of 27 or greater (overweight) who have at least one weight-related condition such as high blood pressure (hypertension), type 2…

is a condition characterised by gradual loss of kidney function over a period of time (months to years). It is also known as Chronic Renal Disease. It is the work of the kidneys to remove waste products and excess fluids from the body through urine. They also balance the levels of salt, potassium and acid in the body. If the kidneys don’t function adequately, wastes can build up in the blood, progressing to develop complications like high blood pressure, anaemia (low…

is a common condition, usually seen in the elderly, of diminished bone mass and low bone weight, which leads to fragile bones. Bones are living tissue constantly being broken down and rebuilt by the body. During childhood and youth, you form new bone faster than you lose old bone. Between the ages of 18 and 30, you reach peak bone mass. As people age, bone loss increases. Osteoporosis occurs when the body doesn’t create enough new bone to keep up with the absorption or…

This new class of drugs unleashes the body's immune system to fight tumors. This seems to solve a century-old mystery of how cancerous cells manage to evade the body's immune system. The drug which Merck will sell under the name of Keytruda was approved by patients with advanced melanoma who have exhausted other therapies.  http://www.nytimes.com/2014/09/05/business/merck-wins-approval-of-novel-immune-system-drug-for-cancer.html?emc=eta1

Hypertension or high blood pressure refers to the amount of force exerted by the blood against the walls of the arteries. A person's blood pressure is considered high when the readings are greater than 140 mm Hg systolic (the top number in the blood pressure reading which shows the force of the blood in the arteries as the heart beats) or 90 mm Hg diastolic (the bottom number shows the force of blood in the arteries as the heart relaxes between the beats). Read…

Menopause refers to the end of a woman’s monthly periods or menstruation. It correlates with the end of a woman’s reproductive ability. The word ‘menopause’ is derived from the Greek word menopausis. Menos means month and pausis is cessation or stop. A woman is said to have menopause only if she has not had her periods for a year (and there are no other health reasons for this). Women go through different symptoms during peri-menopause and menopause phases of their…

Tofacitinib (Xeljanz®) is the first of a unique class of oral kinase inhibitors to be FDA approved for the treatment of rheumatoid arthritis (RA). Tofacitinib is a selective inhibitor of Janus kinase (JAK) enzymes. these enzymes mediate signaling for several important cytokines that cause the inflammation in Rheumatoid Arthritic patients.  http://www.hopkinsarthritis.org/arthritis-news/tofacitinib-fda-approved-oral-biologic-for-rheumatoid-arthritis/