Tofacitinib: A novel oral treatment for rheumatoid arthritis

Submitted by Dr S. Patel on 6 September 2014

Tofacitinib (Xeljanz®) is the first of a unique class of oral kinase inhibitors to be FDA approved for the treatment of rheumatoid arthritis (RA). Tofacitinib is a selective inhibitor of Janus kinase (JAK) enzymes. these enzymes mediate signaling for several important cytokines that cause the inflammation in Rheumatoid Arthritic patients. 

http://www.hopkinsarthritis.org/arthritis-news/tofacitinib-fda-approved-oral-biologic-for-rheumatoid-arthritis/

Changed
06/Sep/2014
Community
Muscle, Bone and Joint (earlier named Arthritis)
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Arthritis

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