Skip to main content
Submitted by PatientsEngage on 19 April 2017

WORLD LIVER DAY

Did you know Type 2 diabetes (T2D), insulin resistance, obesity, metabolic syndrome and NAFLD (Non Alchoholic Fatty Liver Disease) are particularly closely related? Dr Parijat Gupte, Consultant Hepatologist or Liver Specialist, provides us with a basic knowledge on NAFLD and what it can signify.

What Is NAFLD?

In simple terms, NAFLD or non-alcoholic fatty liver disease is abnormal or excess accumulation of fat in the liver. Normally, liver does not contain more than 0-5% fat. The most common cause of fatty liver is excess alcohol consumption. As its name suggests, it is the deposition of excess fat in the liver without intake of excess of alcohol(Non Alcoholic).

How it is different from AFLD(Alcoholic fatty liver disease)?

It has clinical resemblances with alcoholic fatty liver disease, and it shares commonalities as far as investigations go as well. It is often difficult to differentiate between the two, specially if the patient does not divulge any history of alcohol intake. Some clinical features (large liver), clues in blood tests -- very high levels of GGT (Gamma-glutamyl transpeptidase), High MCV (Mean corpuscular volume ) -- and other features on liver biopsy may help differentiate the two.

Who is most at risk of getting NAFLD?

Patients who are obese, suffer from diabetes, high cholesterol and hypertension are the ones most at risk. Some lean individuals or those with a family history of fatty liver disease can also develop fatty liver disease. Women with PCOS ( Polycystic ovary syndrome) commonly have fatty liver.

Are all people with diabetes screened for it? Why?

Fatty liver is found in approximately 40% of diabetics. Patients with diabetes should undergo screening for NAFLD. Presence of fatty liver does not necessarily mean serious liver disease, but it needs further investigations and follow up at regular intervals.

Is it a growing concern in the Indian population?

As diabetes has one of the highest records in India and obesity is also on the rise, changing dietary patterns combined with a sedentary lifestyle has resulted in a steady increase of NAFLD cases.

How is it usually diagnosed?

It is best diagnosed on sonography of the liver. One may suspect fatty liver disease if liver function tests done for any reason are found to be consistently abnormal. It may be the cause of liver disease in an individual who has risk factors and does not have any other obvious cause for his liver disease.

What is the common line of treatment?

Slow, progressive and sustained weight loss of about 5-10% of current body weight is the most important and effective line of treatment.

It should also be combined with a moderate degree of exercise. A mix of aerobic (brisk walking etc.) and anaerobic exercise for 30 minutes for at least 3-4 times a week is recommended. Exercise type and duration should be decided after medical assessment and evaluation for heart disease.

Some patients may be helped with Vitamin E or certain group of antidiabetics. But medical therapy is secondary, short term and is advisable only after expert consultation.

What is the biggest complication of a liver disease?

Serious liver disease can occur in about 5- 10% patients who have fatty liver disease. Patients who have fatty liver are at risk of developing coronary artery disease (heart disease) as risk factors for these diseases are common.

Is weight loss surgery recommended for all patients?

Weight loss surgery is recommended only for those who are morbidly obese, or those who are obese and have severe metabolic complications. It should be performed only after medical and dietary approaches have failed or found to be inadequate. Prior evaluation by an endocrinologist, a gastroenterologist, a nutritionist and even a psychiatrist is mandatory before deciding on surgery.

Dr Parijat Gupte is a Consultant Hepatologist or Liver Specialist who works with several hospitals including the Global Hospital in Mumbai.

Changed
Wed, 04/19/2017 - 09:53

Stories

  • Diabetes Management
    You need a healthy meal plan and an exercise regimen. Being active is very important as it helps the body use insulin more efficiently to convert glucose into energy for the cells.  Food and Nutrition  Making the right food choices is very important in managing diabetes. We make it easy for you to eat well and healthily with simple dos and dont’s, tips for creating a healthy plate and examples of low-glycaemic index foods.  Physical Fitness Exercise plays a key role in managing…
  • Diabetes Treatment
    There is a lot you can do to control your diabetes and stay healthy. Take your medication (if prescribed) regularly, whether it is oral medication or Insulin injections. Untreated diabetes is the cause of many complications, such as blindness, heart and blood vessel disease, stroke, kidney failure, impotence in men, nerve damage and diabetic ketoacidosis. Gestational diabetes can cause birth defects.  Complications Unmanaged diabetes can lead to many serious complications that may affect…
  • Diabetes Tests and Diagnosis
    What tests do you need to have done? Your doctor may recommend the following tests: Fasting Plasma Glucose (FPG): This is a blood test that is done first thing in the morning. You have to fast for eight hours before the test. You are allowed to drink water.  If your fasting blood glucose is 100 mg/dL - 125 mg/dL you are considered Prediabetic. If it is 126 mg/dL or more in two or more tests, you are considered to have diabetes. Oral GlucoseTolerance Test (OGTT): This test checks your…
  • Types of Diabetes
    There are different types and stages of diabetes Prediabetes: is when your blood glucose levels are higher than normal but not high enough to be diabetes. Simply put, prediabetes puts you at risk of developing diabetes unless you change your lifestyle and bring down the amount of glucose in your blood. According to the Centers for Disease Control and Prevention (CDC), 15 to 30 per cent of prediabetics develop Type 2 Diabetes within five years if they do not change their lifestyle. But just…
  • Signs and Symptoms of Diabetes
    You could have no symptoms or you could have one or more of the following symptoms. These symptoms are common for both Type 1 Diabetes (earlier called Juvenile diabetes) and Type 2 Diabetes Mellitus. Increased thirst Frequent urination Blurred vision Extreme fatigue  Weight loss Increased hunger Irritability Tingling or numbness in the hands or feet Frequent skin, bladder or gum infections Wounds that don't heal
  • Causes of Diabetes and Risk Factors
    Are you at risk of developing diabetes? Yes if you are: 45 years of age or older Overweight with a BMI (Body mass index) of 25 or over.  Is your waist measurement more than 35cm (for women) and 40cm (for men) Physically inactive Have a close relative with diabetes Have a history of gestational diabetes or delivering an overweight baby (> 9 pounds) Have polycystic ovary syndrome High triglycerides or low HDL (good) cholesterol Have had abnormal blood sugar tests in the past Have heart…
  • 5 Rupees Ayurveda drug BGR-34 for Diabetes approved by AYUSH
    A herbal drug for diabetes that costs Rs.5 per pill, developed by two Lucknow-based Council of Scientific and Industrial Research (CSIR) laboratories, the National Botanical Research Institute (NBRI) and Central Institute for Medicinal and Aromatic Plants (CIMAP), and licensed to Delhi-based Aimil Pharamaceuticals Pvt. Ltd for commercialization, has been launched in parts of north India. The drug, branded BGR-34, is a combination of natural extracts derived from four plant species…
  • Yoga for managing Diabetes - E-book
    Exercise is a key element in managing Diabetes. While some prefer walking or running, others prefer yoga and weight training. You can read how they included Yoga in their regimen. https://www.patientsengage.com/personal-voices/focus-exercise-and-diet-control https://www.patientsengage.com/personal-voices/move-it So we hand picked simple asanas for our members and put it together in this E-book.  You can download it from here: https://www.patientsengage.com/yogabooklet For more…
  • Image text says Superfoods
    5 budget superfoods
    Nutritious foods that give you the most bang for your buck. By Dietitian and Diabetes educator Ujjwala Baxi When we hear ‘superfoods’, we think quinoa, blueberries, salmon, chia seeds etc thanks to clever marketing and hype. These are not only expensive, but can be hard to get hold of, especially in India. The good news is that there are ‘superfoods’ that are readily available and affordable, but are often ignored. They pack as much punch as the much-touted superfoods but are overlooked as…
  • Manage High Blood Pressure With Our 10 Clear Tips
    Managing high blood pressure is an important aspect of health management since it can lead to many issues - kidney disease, heart disease, cardiovascular disease, etc. We address questions on - What to eat? How much salt is ok? Is it ok to drink? What does Vitamin D have to do with it? And more. 1. What is considered high blood pressure? A reading of 120/80 mmHg is considered normal. A blood pressure reading of 140/90 mmHg or higher is considered high blood pressure. If your blood…